No one goes through life unscathed. It’s essential to navigate challenging moments and cultivate resilience.

Hyun-Joo南
Assistant Professor

  • 教师
Biological and Environmental Sciences
Contact Hyun-Joo
办公室
Science Building 215
Related Department
Biological and Environmental Sciences
家乡
Seoul, South Korea
大学主要
Cell and Developmental Biology

Dr. Hyun-Joo南 has enjoyed participating in research since her years as an undergraduate student. She is excited to pursue her passion for research at A&移动商务. In addition to her research interests, 不结盟运动 spends more time in the classroom than in previous years. She utilizes innovative pedagogical methods and technologies to adapt her courses to ever-evolving student demographics and needs. She aspires to help students realize and achieve their full potential.

A Conversation with Dr. 不结盟运动

Who has been a role model for you? How has this person positively influenced you?

Among the many role models in my life, two stand out. From my father, 不结盟运动 Doo Hee, I learned the essence of leading a principled life. From my mentor, Mavis Agbandje-McKenna, I gained insights into being a principled researcher.

What is an important life lesson you have learned?

No one goes through life unscathed. It’s essential to navigate challenging moments and cultivate resilience.

Tell me about your lab and current research interests.

My research lab is focused on creating affordable insulin, developing inhibitors for the FOXC2 protein as potential treatments for advanced cancers and designing AAV gene therapy vectors targeting the nervous system. Our research focuses on the structure-function relationships of viruses, proteins and protein-DNA complexes, with the goal of engineering these molecules for biotechnological applications.

We utilize a combination of X-ray crystallography, biochemistry and molecular modeling to investigate molecules that regulate gene expression in cancer cells and the use of virus particles in gene delivery systems. 最终, our objective is to understand how structure dictates function to pave the way for innovative therapeutic treatments for diseases.

教育

  • Ph.D., Cell and Developmental Biology, Harvard University
  • M.Ed., Biology 教育, Seoul National University
  • B.S., Biology, Seoul National University

Academic Positions

Professional Associations

Recent Publications

  • 郑,B.Seltzsam, S.,王,C., Schierbaum, L.施耐德,S.吴,C. W.戴,R., Connaughton, D. M.中山,M.美国,美国.斯蒂奇,N.马内,S.鲍尔,S. B., Tasic, V.,南,H. J.史瑞尔,S., and Hildebrandt, F. (2022) Whole exome sequencing identifies FOXL2, FOXA2, and FOXA3 as candidate genes for monogenic congenital anomalies of the kidneys and urinary tract. Nephrol Dial Transplant, 37,18233-1843
  • 李,年代.普拉丹,L.阿舒尔,S.乔希,A.,南,H. J. (2019) Crystal Structure of FOXC2 in Complex with DNA Target. ACS Omega 4, 10906-10914
  • 卡斯塔涅达,M.陈,L.普拉丹,L.,李,S.蔡恩,R.李,Y.林,H. S.,南,H. J.李,J. (2018) A Forkhead Box Protein C2 Inhibitor: Targeting Epithelial-Mesenchymal Transition and Cancer Metastasis. Chembiochem 19, 1359-1364
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